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Axonyx, Inc. (OTC Bulletin Board/AXYX) is engaged in the
discovery, acquisition, & development of proprietary pharmaceutical
compounds & new technologies useful in the diagnosis & treatment
of cognitive disarders, primarily Alzheimer's Disease (AD).
The brains of deceased AD sufferers show the presence of plaques
& tangles in & around nerve cells & the shrinkage of sections of
the brain. The plaques are a toxic form of a protein called beta-amyloid,
deposited in & around nerve cells & on the walls of blood vessels
in the brain of infected individuals. Keeping the plaques from forming,
or dissolving them with amyloid inhibiting peptides is one of the
three breakthrough strategies AXYX is working on.
Patent #5,948,763 was recently issued to New York University for
a novel platform technology for treating AD. AXYX, which collaborated
with Drs. Blas Frangione & Claudio Soto-Jara at the New York University
School of Medicine to develop the technology, holds a world-wide
exclusive license to the technology covered by this patent, which
is also the subject of AXYX's joint development agreement with the
large Swiss-based biotech company Ares-Serono.
AXYX has also cleared regulatory requirements to commence Phase
I U.S. human trials with Phenserine, its lead AD compound, developed
by the Laboratory of Drug Design & Development of the National Institute
of Aging/National Institutes of Health. Worldwide rights to Phenserine
was licensed to AXYX from the U.S. Public Health Service in 1998.
In addition, AXYX has a joint development agreement with the Dept.
of Pathology at the University of Melbourne in Australia for a proprietary
technology for a diagnostic test for AD (up to now, no conclusive
diagnosis of AD can be made before the patient dies).
These three paths hopefully may greatly alleviate the terrible
effects of Alzheimer's Dusease, the 4th leading cause of death in
the U.S. AXYX just raised $4.25 million in a private placement,
which fulfills the necessary requirements for a NASDAQ Small-Cap
listing. Call Linda Strascina at AXYX @ 212-688-4770, fax 212-688-4843,
or write 750 Lexington Ave., NY, NY 10022, or call AXYX's IR firm
@ 904-409-0200, fax 904-409-0043, or e-mail: invrel@ix.netcom.com
www.axonyx.com [R-6; M-6; L-8]
Digital Lava, Inc. (AMEX/DGV) does for video today what
wordprocessors did for words in the late 1980s. Founded in 1995,
DGV, which went public 2/17/99, is a leader in the convergence of
software related technologies that organize & allow for the rapid
manipulation of video with other data. It does previously difficult
& expensive video solutions at low cost.
Its software products & services are sold to Fortune 1000 companies
for use in corporate training, communications, & sales & marketing
applications. Its VideoVisorTM software allows the user to organize
video content. It also allows one to link video to other types of
files, & publish video on CDs or "stream" it over the Internet or
a company's intranet. I ran the video demo -- ask for a copy.
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DGV is targeting the $50 billion business & training software market
(expected to be $100 billion in five years), plus the $28 billion
training & education market. It expects to leverage the growing
demand for business, video training, communications, & distance
learning applications with its video publishing technology.
Its customers & partners include Cisco, Dell, Microsoft, Lotus,
InterVu, RealNetworks, Prudential, Shell Chemical, Zurich-American
General Insurance, & Ardent Software.
DGV is emerging from its R&D stage. Sales are just starting, &
gross margin on those beginning sales is over 80%. At 6/30/99, current
assets were $8,938,140 & current liabilities only $286,366. Recently
appointed CEO Robert F. Greene says "We have a four pronged
approach to achieving our growth objectives. We intend to focus
our business model on a mix of services & software; target key markets
in the high tech, financial & healthcare industries; develop strategic
alliances; & create opportunities in developing technologies such
as broadband Internet & digital settop boxes."
Call DGV @ 888-222-5282, fax 310-306-3373, or write 13160 Mindanao
Way, Suite 350, Marina Del Rey, CA 90292. Or call Financial Relations
Board, DGV's IR company @ 310-442-0599, fax 310-442-0595, or write
12121 Wilshire Blvd., Suite 401. Los Angeles, CA 90025. www.digitallava.com
[R-6; M-7; L-8]
One Stop.com, Inc. (OTC Bulletin Board/OSCR) was founded
2/97, & restructured a year ago. It has operated two units; (1)
e-commerce via www.shopss.com; & (2) its communications division,
developer of Internet applications for fax & IP telephony.
The Shopss.com, Inc. subsidiary (www.shopss.com) reported new
orders of $60 million, revenues of $20 million, & net income of
$6 million for the quarter ended 9/30/99.
The communications division reported revenues of $80 million,
much of which resulted from OSCR's partnership with CMR Communications
Ltd., an Israeli based firm that develops & markets real-tme fax
with real-time confirmation for IP technology.
Moshe Brown, CEO of CMR Communications says "We are now
installing over 1,000 gateways & 20,000 ports worldwide to support
the OSCR/CMR network. Our network, which will act as a telecommunications
termination partner, will target millions of new customers & will
offer an array of services, including our revolutionary fax-to-e-mail
service, which allows businesses & individuals to fax documents
to any e-mail address in the world."
OSCR recently sold its e-commerce unit to AMCI International,
Inc. (OTC Bulletin Board/AMMN), a fully reporting 12g company, which
changed its name to Shopss.com, Inc.
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